Charles N. Krome, DO – Regenerative Orthopaedic Medicine
Shore Orthopaedic University Associates is pleased to offer the latest treatment in
Regenerative Orthopaedic Medicine… Stem Cell Therapy
Stem cells are undifferentiated cells that can differentiate into specialized cells that are capable of playing a role in helping the body repair and rejuvenate itself. They can change themselves into cells such as chondrocytes capable of cartilage repair, myocytes which are capable of muscle repair, tenocytes which are capable of tendon repair, as well as cells capable of bone and even nerve repair. Stem cells can come from many different sources in our own bodies including, blood, fat, bone marrow, dental pulp, as well as many other tissues. Stem cells can also come from sources outside our own bodies including embryonic tissue, amniotic tissue, and umbilical cord blood. At Shore Orthopaedics, Dr. Charles Krome (who has been performing regenerative medicine procedures since 2008) uses stem cells derived from the umbilical cord blood donated from healthy mothers, along with a patient’s own platelet rich plasma, to treat a variety of orthopaedic/sports medicine conditions including osteoarthritis of the knee, hip, shoulder, ankle, etc., rotator cuff tears, tennis elbow and other tendonopathies of the body, plantar fasciitis, meniscal and ligament injuries, as well as many other musculoskeletal conditions.
There is no surgery or invasive procedures done to the patient. No bone marrow aspiration. No liposuction. The cells are ordered direct from a tissue bank which screens the donated cord blood for diseases and the cells come specifically for each patient’s procedure the morning of the stem cell injection. The cells are thawed and mixed with the patient’s own platelet rich plasma to maximize healing capability, then injected directly into the treatment area. Most injections are done under ultrasound guidance to ensure appropriate delivery into the joint being treated. There is no HLA matching which means the cells will not illicit an immune response from the patient. The potential for healing and improved quality of life is very high with umbilical cord derived stem cells with minimal risks to the patient.
To see if you are a candidate for this exciting regenerative therapy, please schedule a consultation with Dr. Krome to discuss your therapeutic options. Appointments available in our Somers Point, Galloway and Cape May Court House offices.
Regenerative Medicine – Cord Blood Stem Cells FAQ’s
Regenerative medicine offers much promise for those suffering from several disease states. It is a method of using our own natural healing properties in living a better quality of life. Stem cells are presently the largest target in the regenerative medicine area.
Stem cells are naive cells that have the ability to divide indefinitely. They may functionally change into any cell in our body and can integrate to the target tissue, either in the presence or absence of damage. Stem cells are “undifferentiated” cells, which allow them to develop into another type of cell that is required to repair or replace damaged tissue. Stem cell therapy can repair tissues that are too damaged to heal on their own. Stem cells can stimulate the formation of cartilage, tendon, ligaments, bone and fibrous connective tissue. Stem cell therapy is in the spectrum of cutting-edge therapeutic techniques used to naturally treat and heal the cause of a painful condition rather than masking the symptoms. Stem cell therapy stimulates and accelerates your own body’s natural ability to heal itself.
Osteoarthritis is the most common cause of chronic joint pain. Osteoarthritis involves the entire joint, including the nearby muscles, underlying bone, ligaments and connective tissue. In osteoarthritis, the supportive tissue called cartilage degenerates, leading to inflammation and pain. This type of arthritis is common in shoulders, hips, knees, hands and feet. Patients will often complain of joint stiffness, throbbing, and swelling. There is no cure for osteoarthritis, but regenerative medicine therapies such as stem cell therapy is a new generation of treatment that has been proven to be safe, effective, and have lasting results.
Rethinking and evolving science using cutting-edge technologies have led to the most potent and vibrant form of stem cells, umbilical cord blood-derived cellular allograft tissue. Umbilical cord blood contains a beneficial blend of cytokines, growth factors, and stem cells that ensure a rich microenvironment to foster tissue regeneration and cellular growth.
Cord blood regenerative medicine products contains primitive undifferentiated stem cells and additional growth factors which are beneficial for repair, growth and healing. The release of growth factors that aid in the formation of new blood vessels, activation of endogenous stem cells, modulation of the immune system and growth of cells and tissue. In stem cell therapy, new stem cells are introduced into the body, and their capacity to differentiate or turn into specialized cells may allow them to repair diseased or injured tissues. They also proliferate or renew themselves many times, which can provide an ongoing supply of healthy cells. Stem cells are “intelligent.” They can move through the body to where they are needed and communicate with other cells. Research indicates that mesenchymal stem cells may offer other important therapeutic properties including immunomodulation, anti-inflammatory functions, infection-fighting properties and cell rescue actions. The array of benefits related to umbilical cord blood-derived allografts is supported through the successful transplantation and coordination of multiple components. There is a careful orchestration of the ratios of cytokines, growth factors, exosomes and stem cells naturally occurring in umbilical cord blood. This naturally occurring balance of cytokines and growth factors make umbilical cord blood a great resource for allograft tissue geared towards bone growth and tissue regeneration.
Umbilical cord stem cells contain mesenchymal stem cells (MSCs). They come from safe, reliable hospital sources via a non-invasive, simple, and painless procedure. The cord blood fluid allograft tissues are procured through fully tested and consented donors. Every donor is subjected to comprehensive infectious disease panels that surpass federal and industry standards, ensuring safe allografts. Umbilical cord-derived mesenchymal stem cells are provided by hospitals. All donated cord blood is delivered directly to the lab for production. As no potentially risky or painful surgery is required, extraction of umbilical cord blood is the least invasive and safest option of sourcing stem cells. Research has shown the cord blood stem cells are not susceptible to malignant transformation in a serum-free medium, making them safe for therapeutic use in patients. The stem cells are screened in compliance with FDA, cGMP (Current Good Manufacturing Practice) standards, which regulate quality and safety in the production of medication.